Season 2

The second season of the American television medical drama Grey's Anatomy commenced airing on the American Broadcasting Company on September 25, 2005, and concluded on May 15, 2006. The season was produced by Touchstone Television, in association with Shondaland production company and The Mark Gordon Company, the showrunner being Shonda Rhimes. Actors Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers, and T.R. Knight reprised their roles as surgical interns Meredith Grey, Cristina Yang, Izzie Stevens, Alex Karev, and George O'Malley, respectively. Previous main cast members Chandra Wilson, James Pickens, Jr., Isaiah Washington, and Patrick Dempsey also returned, while Kate Walsh, who began the season in a recurring capacity, was promoted to series regular status, after appearing in seven episodes as a guest star. The season continued to focus on the surgical residency of five young interns as they try to balance to the challenges of their competitive careers, with the difficulties that determine their personal lives. It was set in the fictional Seattle Grace Hospital, located in the city of Seattle, Washington. Whereas the first season put the emphasis mainly on the unexpected impact the surgical field has on the main characters, the second one provides a detailed perspective on the personal background of each character, focusing on the consequences that their decisions have on their careers. Throughout the season, new story lines were introduced, including the love triangle between Meredith Grey, Derek Shepherd, and Addison Montgomery, the main arc of the season. Also heavily developed was the story line involving Izzie Stevens' relationship with patient Denny Duquette, which resulted in critical acclaim and positive fan response.

Season episodes list 2

S02E01

S02E01 : Raindrops Keep Falling on My Head 8.56/10 (aired on 09/25/2005)

Picks up where the last episode left off. Meredith attempts to work with Addison Shepard. George is…
S02E02

S02E02 : Enough is Enough (No More Tears) 8.37/10 (aired on 10/02/2005)

There's tension between Meredith and Addison. We find out why Derek and Addison aren't together.…
S02E03

S02E03 : Make Me Lose Control 8.75/10 (aired on 10/09/2005)

Cristina and Meredith try to figure out if Cristina should tell Burke that she's pregnant right…
S02E04

S02E04 : Deny, Deny, Deny 8.55/10 (aired on 10/16/2005)

As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her…
S02E05

S02E05 : Bring the Pain 8.74/10 (aired on 10/23/2005)

Cristina goes right back to working right after being discharged. Izzie isn't talking to Alex.…
S02E06

S02E06 : Into You Like a Train 9.16/10 (aired on 10/30/2005)

Train Wreck victims come to Seattle Grace and all staff gets called in. Everyone deals with really…
S02E07

S02E07 : Something to Talk About 8.45/10 (aired on 11/06/2005)

Cristina, Izzie and Meredith take care of Shane, a man who appears to be crazy and claims that he…
S02E08

S02E08 : Let it Be 8.27/10 (aired on 11/13/2005)

Meredith tries to avoid the Shepherds. Cristina and Burke go out on a date and end up getting…
S02E09

S02E09 : Thanks for the Memories 8.64/10 (aired on 11/20/2005)

It's Thanksgiving at Seattle Grace Hospital but the holiday's festivites are less than in order.…
S02E10

S02E10 : Much Too Much 8.36/10 (aired on 11/27/2005)

Dorie Russell is waiting for quintuplets, all 5 girls. Her husband seems more concerned than she is…
S02E11

S02E11 : Owner of a Lonely Heart 8.37/10 (aired on 12/04/2005)

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a…
S02E12

S02E12 : Grandma Got Run Over by a Reindeer 8.46/10 (aired on 12/11/2005)

The holiday season has started but not everyone is in a festive mood. This is Alex's last day in…
S02E13

S02E13 : Begin the Begin 8.55/10 (aired on 01/15/2006)

Cristina is bothered by a new year's mandatory work limit. Izzie patient, Denny Duquette, wants two…
S02E14

S02E14 : Tell Me Sweet Little Lies 8.35/10 (aired on 01/22/2006)

Meredith and Cristina lie to each other and themselves about their relationships with McDreamy and…
S02E15

S02E15 : Break on Through 8.65/10 (aired on 01/29/2006)

All the nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves.…
S02E16

S02E16 : It's the End of the World 9.47/10 (aired on 02/05/2006)

An explosive case arrives at the O.R. that might endanger all the lives of the people working…
S02E17

S02E17 : As We Know it 9.47/10 (aired on 02/12/2006)

Derek is still operating when he finds out about Meredith's current situation. Meredith is freaking…
S02E18

S02E18 : Yesterday 8.65/10 (aired on 02/19/2006)

Derek and Addison's relationship is rocked to the core when a former friend comes to Seattle Grace…
S02E19

S02E19 : What Have I Done to Deserve This? 8.46/10 (aired on 02/26/2006)

Meredith and George are experiencing morning-after tension at home and at work and it has the rest…
S02E20

S02E20 : Band Aid Covers the Bullet Hole 8.36/10 (aired on 03/12/2006)

The doctors are up to their necks in their usual levels of drama. Meredith is dealing with the…
S02E21

S02E21 : Superstition 8.46/10 (aired on 03/19/2006)

After a series of deaths at the hospital some of the staff become very superstitious. Izzie worries…
S02E22

S02E22 : The Name of the Game 8.36/10 (aired on 04/02/2006)

Meredith and Izzie take up knitting. Derek operates on Andrew, a spelling bee champ with a serious…
S02E23

S02E23 : Blues for Sister Someone 8.27/10 (aired on 04/30/2006)

Addison's patient is a Catholic mother of seven. Addison gets in trouble after learning that the…
S02E24

S02E24 : Damage Case 8.66/10 (aired on 05/07/2006)

The staff attends to an intern from another hospital who has short-term memory loss. This intern,…
S02E25

S02E25 : 17 Seconds 9.16/10 (aired on 05/14/2006)

George and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with…
S02E26

S02E26 : Deterioration of the Fight or Flight Response (1) 9.15/10 (aired on 05/15/2006)

Denny needs a heart or else. Izzie and George go crazy trying to get him one. Derek has the life of…
S02E27

S02E27 : Losing My Religion (2) 9.37/10 (aired on 05/15/2006)

This episode is the second part of a two-hour season finale. Richard tries to get information from…